October 27, 2020
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For the past few years, non-surgical cosmetic procedures have been riding on a steady wave of popularity. What’s more, the International Society of Aesthetic Plastic Surgery (ISAPS) reports that people prefer minimally-invasive treatments over surgical ones. As a result, the popularity of Botulinum toxin injections and dermal fillers has scored an annual increase by a combined average of 14.5%. We’re here to help you answer one simple question: Botox vs fillers – Which one is better for you?
Although filler injections and Botox solutions both have fast effects, they are two different types of products. Therefore, they have different properties and longevity. So, to help you choose the right treatment for you, we’ll need to explore their:
Main differences
Effects longevity
By the end of this article, you’ll feel like an expert on non-invasive cosmetic procedures. Moreover, you’d be able to solve the Botox-or-fillers dilemma.
While Botox and dermal fillers are applied through injection, they are don’t have a lot of things in common. For starters, they don’t have the same active ingredients. Also, the two products work in a completely different way. Let’s look at the main differences between Botulinum toxin and soft-tissue fillers.

What Are Fillers?

The versatility of skin fillers available on the market is impressive to many people. Today, these injectables use trademark formulas. Furthermore, they can be subdivided based on the type of ingredients they contain:

  • Hyaluronic acid (HA): Juvéderm, Restylane, Belotero
  • Calcium hydroxylapatite (CaHA): Radiesse
  • Poly-L-lactic acid (PLLA): Sculptra
  • Polymethyl-methacrylate microspheres (PMMA): Bellafill
  • Polyalkylimide (Bio-alcamid): Aquamid

Some of the dermal filler injections above have temporary effects and others — semi-permanent and permanent. Although all types add volume under the skin, they often have unique properties of their own.

For instance, Hyaluronic Acid fillers deliver long-lasting skin hydration. In comparison, those that feature CaHA remove not only wrinkles but also stimulate collagen production in the skin.

If you want to undergo an all-around rejuvenation treatment, your doctor may need to use different filler types and brands. Since each product has a unique concentration and properties, most of them target several specific cosmetic problems. For example, filler injectables that work for deep nasolabial folds are not suitable for the correction of fine smile lines. For one thing, these products are injected into two different layers of the dermis.

Even though dermal fillers are not interchangeable, they do have plenty of things in common. For the most part, they provide patients with immediate effects. Also, they have a similar modus operandi — namely, filling lines and increasing the volume under the skin. Best of all, filler injection treatments require almost no downtime.

What Is Botox?

Contrary to what many people think, Botox is not a type of product. In reality, it is a brand of Botulinum toxin injection. Since Allergan’s Botox was the first product of its kind, its brand name is now commonly used as a generic word.

As mentioned, Botox-like injectables contain Botulinum toxin — a neurotoxin that relaxes the muscles. Unlike dermal fillers, this cosmetic solution does not add volume under the skin. Instead, it prevents muscles from contracting. As a result, the appearance of expression wrinkles improves.

One downside that Botox has compared to filler injections is that it does not work instantly. Therefore, you’ll need to wait a few days to see the anti-wrinkle effects of the treatment.

Although all Botulinum toxin products feature the same neurotoxin, they differ in many ways. For example, some brands like Ipsen’s Dysport offer faster onset than Botox and Bocouture. Furthermore, products such as Merz’s Xeomin have more limited spread. So, they are more suitable for cosmetic procedures as they offer more accuracy than those with a wider spread.

Another major difference between Botox-like products has to do with the way their units are measured. Manufacturers rely on unit measurement methods of their own. Consequently, their recommended dosage is not interchangeable.

Last but not least, almost all Botox injections come in the form of powder. As a result, plastic surgeons need to dilute them with sterile saline before injecting them. However, there are now liquid options such as Innotox. Since they come in a ready-to-use form, they are considered to deliver more consistent results.


Botulinum toxin injections the more affordable option since US patients pay $385 per Botox session on average. In comparison, one dermal filler procedure can be twice as expensive.

However, these are just average estimates. The end price of your treatment may be considerably higher or lower, depending on:

  • The effects you want
  • Your provider
  • The amount of product that needs to be used
  • Target zone
  • The severity of your cosmetic problem


Even though there are many myths about the safety of these two anti-wrinkle products, they are generally hide no serious risks . Moreover, the US Food and Drugs Administration has approved the cosmetic use of several filler and Botox-like injections. Some of these FDA-approved products include dermal fillers like Restylane and Juvéderm and Botox solutions such as Botox and Dysport.

Still, both categories of injectables come with their own set of side effects. Fortunately, most of the unwanted effects they cause are harmless and mild. In most people, they disappear within hours or a couple of days after the procedure.


Botox is the most famous Botulinum toxin injection, while Juvéderm is the most popular Hyaluronic Acid filler. Probably, that’s the reason some people ask, ‘Which one is better Botox or Juvéderm?’

Hopefully, this article has shown you that these are two completely different products. The only thing Botox and fillers like Juvéderm have in common is that there are both top-quality rejuvenating injectables. Indeed, it’s not a question of which of these two brands is better for you, but which treatment will work best for you.


In conclusion, to choose the right minimally-invasive treatment for you, focus on what you want to treat. Botox-like products and fillers may differ in price, formula, and durability. Nevertheless, these differences would not matter because the two treatments are not interchangeable. Botulinum toxin injections work best on moderate-to-severe wrinkles around the eyes, while dermal fillers have multiple anti-aging uses.

The winner in the Botox vs Fillers battle depends entirely on your cosmetic correction needs. However, don’t try googling fillers or Botox near me if you still struggle to make a pick, contact a board-certified plastic surgeon. Such a professional will choose the best treatment option for you.

Dr. Anthony Brooks, MD PhD
About Dr. Anthony Brooks, MD PhD

Dr. Anthony Brooks, MD PhD, is a renowned, board-certified plastic surgeon who specializes in minimally invasive skin rejuvenation procedures. He studied at the University of California, San Francisco (UCSF) and earned an MD in Plastic and Reconstructive Surgery in 1991. Not long after that, Dr. Brooks started training in the United Kingdom as a plastic surgeon and it was there that he was awarded with a PhD. His clinical interests include aging face surgery, dermal fillers, laser therapy and neuromodulators (e.g. Botox).

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